AMR kills 33,000 Europeans every year (Lancet)

Anti-microbial resistance (AMR) is a clear and present danger

The rise of AMR has been accelerating the past years. This has been proven by many research studies and governmental Initiatives. A recent article published in The Lancet on November 5th 2018 states that as many 33 000 Europeans die every year from AMR related bacterial infections. This elevates the disease burden to be on par with the combined deaths of influenza, tuberculosis and HIV/AIDS. 

The study furthermore states that a majority of the infections and deaths are associated with the healthcare system, which is a major challenge for public health. 

"We estimated that 63,5% (426 277 of 671 689) of cases of infections with antibiotic-resistant bacteria were associated with health care, resulting in 72,4% (23 976 of 33 110) of attributable deaths and 74,9% (127 of 180) of DALYs* per 100 000 population. This finding suggests that the health effects of infections with antibiotic-resistant bacteria predominantly occur in hospitals and other health-care settings.”

Learn more about the report here:

Less bacteria in the air means less risk for infections - Opragon case

The new Lancet article is only one in a long line of studies that point to the importance of ultra-clean air in operating rooms as a means of reducing the risk of Surgical Site Infections (SSIs), since high bacteria levels in the air during surgery is one of the leading causes of SSIs. (

Avidicare works with the mission “Towards Zero Infections” which summarises our aim to eliminate the risk of Surgical Site Infections (SSI) within the healthcare system. The Avidicare Opragon system has a scientifically proven capability to lower airbone bacteria levels during surgery, and with antibiotics being less and less effective, this capability will increase in importance. Since when antibiotics fail to treat the infection, it will be more important than ever that the bacteria do not enter the wound in the first place. It is also important to combine ultra-clean air with modern hygenic protocol and antibiotics.

Learn more on how Avidicare can help you fight SSI and join us in our mission on  

*Disability Adjusted Life Years - DALY

First clinical Avidicare Opragon installation in Potsdam, Germany

First clinical Avidicare Opragon installation in Potsdam, Germany

The Oberlinklinik in Potsdam launched the first two of four Avidicare Opragon systems on October 15th 2018. This is another great example of a collaboration to reduce bacteria levels during surgery with leading orthopaedic clinics in Northern Europe. 

This successful launch is part of the greater ongoing Avidicare expansion in the DACH and Benelux regions respectively  where Sint Maartens Klinik in Nijmegen and Clinica Luganese Moncucco, Lugano, Switzerland are two additional examples. 

The Oberlinklinik launch event was featured in the Potsdam TV network "Hallo Potsdam” please see link below:

Please learn more on the Avidicare Opragon system on

Nov 23 - Join Opragon Workshop in Oberlinklinik, Potsdam

Endlich ist es soweit, die neuen Operationssäle im Oberlinhaus sind in Betrieb. Wir möchten Sie herzlich zum Avidicare Workshop in Potsdam am 23. November einladen. Dort erwarten Sie interessante Vorträge und die einzigartige Möglichkeit das innovative Opragon-System von Avidicare in einem Operationssaal zu erleben. Wir freuen uns darüber, dass wir führende Experten für die Vorträge des Workshops gewinnen konnten. Die Themen der Vorträge entnehmen Sie bitte dem Save-the-Date Flyer (DOWNLOAD).

Die Teilnehmerzahl für die Besichtigung des Opragon ist allerdings begrenzt, daher bitte ich Sie, mich zeitnah via zu kontaktieren, um Ihre Einladung zu bestätigen.

Research confirms benefits of Opragon compared to LAF and mixing ventilation

The Royal Institute of Technology in Stockholm (KTH) has investigated the new Temperature controlled AirFlow (TAF) being used in the Opragon® operating room ventilation and compared it with the two conventional technologies (LAF and TMA). The super-computer based numerical simulations confirmed that Opragon creates ultra-clean conditions in the whole operating room using significantly less air than LAF. TMA could not maintain ultra-clean levels. It also showed that only increasing the airflow rate (ACH) was not efficient to improve the removal of bacteria. Access the report here, or mail for a copy of the article:

Getting the hospital you deserve

The Dutch health-care magazine FMT has interviewed key stakeholders at the leading orthopedic clinic SMK, who share the story of the integrated ORs from Avidicare and Optimus.

That Opragon has been chosen for an orthopedic hospital is an outstanding choice. It was mainly guided by the positive experiences of Swedish hospitals. Koen Defoort, orthopedic surgeon at SMK: "We went to see Opragon in Swedish hospitals in which implantations are being carried out on a large scale. The experiences were unanimously positive with low infection rates. What further convinced us were the bacteriological measurements - and not with particle counts. The results were very favorable. We already have low infection rates (1-1.5%) and we are convinced that these can certainly be achieved in the new ORs and may be improved somewhat.”

Prof Mark van Houdenhoven, chairman of the executive board at SMK, concludes: "We are working very hard with a lot of people, our position is that every hospital gets the hospital that it deserves." To learn more, check this link.

Blog - Superbugs are changing healthcare

Airborne bacteria is a main source of the feared Surgical Site Infection (SSI). They cause many deaths and suffering that also consumes health care resources that could have been used better. Today, healthcare relies on curing infections using antibiotics, but as superbugs resistant to drugs are rapidly becoming more common, we need to redesign how care is given. Prevention will become much more important, which in the case of SSIs means investing in innovations such as ultra-clean air systems that prevent the bacteria from entering the wounds in the first place.

Tags: Airborne bacteria, SSI, AMR, Ultra-clean air during surgery, Opragon, Avidicare, SVT, American Journal of Infection Control

Anti-microbial resistance is a growing health risk today and in the future

The current development of AMR is growing into a global worry. The current levels of SSIs are kept to somewhere between 1-5% with the use of antibiotics during and after surgery. The long-term challenge is that antibiotics are experiencing reduced or completely lost effectiveness due to superbugs. They are bacteria that cannot be killed by antibiotics.

In fact, the Swedish national television recently ran a special report on SSIs that pointed to the importance of antibiotics:

”The WHO estimates that ten million people die every year as a result of bacterial infections that antibiotics can’t kill. 25 000 of them live in Europe. Approximately 400 of them are Swedes, according to the Swedish National board of health and welfare” (, 2018)

It is also important to note that antibiotics are not only essential for fighting infections but also crucial for enabling certain treatments, including cancer.

”(…) antibiotics is crucial in the healthcare system, not only for treating infections, it is also a pre-requisite for a successful outcome of many different treatments and surgeries, such as chemotherapy.” (, 2018)

The special report pointed to the risk of performing surgery at all on patients that are infected with superbugs.

”-Today we take many things for granted. To be able to get a hip replacement, for example, we might not be able to do that in the future. This is especially true if the patient carries a superbug, then we may have to refrain from at all performing the surgery." (, 2018)

The right OR ventilation system reduces airborne bacteria levels during surgery

At Avidicare we have more than ten years’ of experience from installing more than 130 OR ventilation units at leading academic hospitals in Northern Europe. We have during this period amassed a weight of scientific evidence illustrating the effectiveness of the Opragon system to create ultra-clean air conditions during surgery. This is in line with scientific recommendations, such as recently published in the Journal of Infection Control.

“Future considerations should be given to institutional investment in innovative air purification technologies as an adjunctive strategy to enhance current engineering controls in an effort to reduce the risk of Perioperative Joint Infections” (AJOIFC, 2018)

There are additional scientific articles illustrating the effectiveness of the Opragon ventilation system as well as comparison with other technologies in the market today.

Learn more about how you and your organization can reduce the risk of Surgical Site Infections on or through the linked resources below.

Further reading

There are many relevant publications that illustrate the importance of ultra-clean air during surgery to reduce the risk of infection from superbugs and AMR side effects.


The WHO information resource on antimicrobial resistance:

Swedish national broadcasting organisation

The Journal of Hospital Infection

Temperature-controlled airflow ventilation in operating rooms compared with laminar airflow and turbulent mixed airflow, M.Alsved et al, The Journal of Hospital Infection, 2018

American Journal of Infection Control

“Environment of care: Is it time to reassess microbial contamination of the operating room air as a risk factor for surgical site infection in total joint arthroplasty”, Parvizi et al, American Journal of Infection Control, 2017

Berlin Students Study Opragon

Avidicare was invited by the students from OSZIMT in Berlin to present and discuss around the Opragon system compared to traditional ventilation solutions in German operating theatres. A few of the students also had the opportunity to visit an Opragon workshop at OTH-Weiden led by Prof. Dr. med. Clemens Bulitta thus gaining more practical experience. Read their article here. And if you want to learn more as well or even make a visit, just e-mail

One in ten develops an SSI globally - 20% resistant to antibiotics

More than one in 10 (12%) patients around the world develops a surgical site infection within 30 days of gastrointestinal surgery, finds a study* of more than 12,500 people in 66 countries, published in The Lancet Infectious Diseases

Worryingly, more than one in five (22%) of these infections were resistant to the antibiotics given before surgery to ward off infections. 

“These findings begin to characterise the relationship between surgical site infections and global antimicrobial resistance,” says Dr Ewen Harrison, NIHR Unit on Global Surgery at the University of Edinburgh. 

Leading orthopedic clinic chooses Opragon

One of the best orthopedic clinics in the world, The Sint Maartenskliniek in Holland, has chosen Opragon to ensure that their patients and staff get the cleanest and most comfortable air in their six new operating and six lay-up rooms. The Opragon system allows the surgical team increased flexibility in terms of working space, which benefits both patient safety and working comfort. Read more in our press room here.

(Photo from St Jansdaal in Holland, Linda Heller)

Kids get best O.R. ventilation

Avidicare is proud to announce that it is helping the prestigious Queen Silvia’s Kids and Youth Hospital to reduce the risk for Surgical Site Infections by suppling the innovative Opragon ventilation systems to several operating and hybrid operating rooms. Learn more about the cool and futuristic hospital project here and watch their YouTube video (in Swedish).  E-mail for the press release (in Swedish).

New scientific evidence for Opragon

The respected “Journal of Hospital Infection” just published an article comparing the Opragon system to traditional OR ventilation systems. Researchers confirmed that Opragon maintains ultra-clean conditions in the whole OR using less energy and with better working conditions than Laminar Airflow Systems, while also using 28% less energy. Mixed ventilation was not able to create ultra-clean conditions. Read the paper here. (Open access will be available in November.)

The Journal of Hospital Infection is the editorially independent scientific publication of the Healthcare Infection Society. The aim of the Journal is to publish high quality research and information relating to infection prevention and control that is relevant to an international audience.

Saving energy for German hospitals

The fifth edition of KlinerigieMagazin from Viamedica Stiftung is now available for download.

This year’s edition is focused on environmental certifications in hospitals. The articles are a guide for future development in other hospitals.

Please see the article on page 26 regarding the Opragon system by Avidicare “OP-Lüftungssystem für hochreine Luft als Energiekostensparer“ (in German). It explains how Opragon keeps your entire OR ultra-clean using about 30% less energy than traditional LAF solutions.

World is running out of antibiotics

Antibiotic-resistant superbugs are on the rise, and the World Health Organization issued a warning of the lack of new antibiotics under development while the threat of antimicrobial resistance grows.

"Antimicrobial resistance is a global health emergency that will seriously jeopardize progress in modern medicine," says Dr. Tedros Adhanom Ghebreyesus, director-general of WHO. He continues to say "There is an urgent need for more investment [...], otherwise we will be forced back to a time when people feared common infections and risked their lives from minor surgery."

Download the WHO report here.

Opragon cleanest per dollar

According to a new report published by the Swedish Energy Agency, the Opragon operating room ventilation has the best hygiene index. This means that is uses the least amount of energy to maintain ultra-low levels of bacteria in the room, compared to traditional laminar air flow systems as well as mixing systems. Of course, using less energy means spending less money as well as taking care of our nature! The report is available for download at the agency’s home page (Swedish and English), or contact Avidicare for your own copy.

Download your Opragon as a BIM object

Our bestselling Opragon 8 for operating rooms, as well as our Opragon 5 and 6 for preparation rooms, are now available for download as BIM objects. BIM speeds up your design work and ensures that interfaces such as air, power and mechanical attachments are handled in the correct way. Standard file formats are available for use in Revit, ArchiCAD, etc. Please contact to get a download link. 

Antibiotic resistance scares mighty G20 countries

The powerful G20 countries for the first time ever gathered their ministers of health last week. Representing two thirds of the world’s population and 85% of the global economy, the ministers agreed to develop national action plans to stop antibiotic resistance. The meeting was initiated by Germany and global health is from now on a constant on the G20 agenda.

"Antibiotics are one of the most important achievements of modern medicine in the fight against infectious diseases and when it comes to safeguarding surgical procedures. Our ability to fight bacterial infections is, however, increasingly being placed in jeopardy or even becoming impossible due to the global rise in especially dangerous pathogens. If we do not act now, together and across the world, we are heading for a post-antibiotic era. And that will have dramatic consequences for us all." [German Federal Health Minister Hermann Gröhe]

Read more here.